ORCA-Fusion BT Digital CMOS camera


See what you’ve been missing

The ORCA-Fusion BT camera is the pinnacle of scientific CMOS (sCMOS) performance. The specifications are without compromise: ultra-low readout noise, CCD-like uniformity, fast frame rates and back-thinned enabled high QE. But the beauty of the ORCA-Fusion BT is what this combination of exceptional photon detection and collection can do for you. See the dimmest whisper of signal, acquire visually stunning, high S/N images from the fewest photons, capture previously unresolved temporal events and perform computational methods with confidence. The ORCA-Fusion BT is the camera that makes the difficult experiments easy and previously impossible experiments possible.

ORCA-Fusion BT advantages versus other BT CMOS cameras

Exclusive industry leading BT sCMOS performance with trusted Hamamatsu quality and reliability

  • Extremely low readout noise
  • High QE, across a wide range of wavelengths
  • CCD-like uniformity; minimal high readout noise pixels
  • High dynamic range
  • 3 readout speeds
  • Lightsheet readout mode
  • 5.3 Megapixels
  • Both USB 3.0 and high speed CoaXPress interfaces

ORCA-Fusion BT advantages versus EM-CCD cameras

A practical and functional replacement for expensive EM-CCDs with uncompromising sensitivity, speed and versatility

  • Resolution
  • Binning versatility
  • No amplification or excess noise
  • High dynamic range
  • Large field of view


  • Wide-field fluorescence microscopy
  • Time-lapse imaging
  • Spinning disk confocal microscopy
  • Lightsheet microscopy
  • Super resolution precision localization
  • Genetically encoded voltage imaging
  • Optogenetics
  • Single molecule tracking
  • Computational imaging
  • Quantum computing

Time-lapse live cell imaging by low light excitation

Sample: H9c2, Objective lens: Apo TIRF 60XC (NA1.49), ND: 8, Interval: 15 sec


c15440-20up Application example 1

HCS NuclearMask Stains / Exposure 20 ms


c15440-20up Application example 3

MitoTracker / Exposure 500 ms


c15440-20up Application example 2

CellMask Plasma Membrane stains / Exposure 500 ms

Lightsheet Readout Mode [Patented]

PC recommendation

With the introduction of the ORCA-Fusion BT, users are now able to stream 5 megapixel images to their computers 89 frames per second. The computer recommendations for this high data rate can be met by using the guidelines listed this PC Recommendations for ORCA-Fusion BT.


Product number C15440-20UP
Imaging device Scientific CMOS image sensor
Effective number of pixels 2304 (H) × 2304 (V)
Pixel Size 6.5 μm × 6.5 μm
Effective Area 14.976 mm (H) × 14.976 mm (V)
Full well capacity 15 000 electrons *1
Readout speed Fast scan, Full resolution, CoaXPress : 89.1 frames/s
Fast scan, Full resolution, USB 3.0 : 31.6 frames/s(16 bit), 42.2 frames/s(12 bit) , 63.3 frames/s(8 bit)
Standard scan, Full resolution, CoaXPress : 23.2 frames/s
Standard scan, Full resolution, USB 3.0 : 23.2 frames/s
Ultra quiet scan, Full resolution, CoaXPress : 5.42 frames/s
Ultra quiet scan, Full resolution, USB 3.0 : 5.42 frames/s
Readout noise Fast scan : 1.6 electrons rms *1
Standard scan : 1.0 electrons rms *1
Ultra-quiet scan: 0.7 electrons rms *1
Exposure times Fast scan : 17 µs to 10 s
Standard scan : 65 µs to 10 s
Ultra quiet scan : 280 µs to 10 s
Cooling method Peltier cooling
Cooling temperature Forced-air cooled (Ambient temperature: +25 ˚C) : −8 ˚C
Water cooled (Water temperature: +25 ˚C) : −8 ˚C
Water cooled (Max cooling (Ambient temperature: +20 ˚C, water temperature: +20 ˚C)) : Less than −15 ˚C
Dark current 1.0 electrons/pixel/s (cooling temperature: -8 ˚C , Ambient temperature: +25 ˚C)*1*3
1.0 electrons/pixel/s (cooling temperature: -8 ˚C , Water temperature: +25 ˚C)*1*3
0.7 electrons/pixel/s (cooling temperature: Less than −15 ˚C , Ambient temperature: +20 ˚C, water temperature: +20 ˚C)*1*3
Dynamic range 21 400:1 *1*2*4
External trigger mode Edge, Level, Sync readout, Start, Global reset edge, Global reset level, Programmable
External trigger signal routing SMA
External trigger delay function 0 μs to 10 s (1 μs step)
Trigger output Global exposure timing, Trigger ready, Low, High, 3 programmable timing outputs
External signal output routing SMA
Interface CoaXPress (Dual CXP-6) and USB 3.0 Super Speed *5
A/D converter 16 bit, 12 bit, 8 bit
Lens mount C-mount (standard), F-mount (C15440-20UP01)
Power supply AC 100 V to AC 240 V, 50 Hz/60 Hz
Power consumption Approx. 155 VA
Ambient operating temperature 0 °C to +40 °C
Ambient storage temperature -10 ℃ to +50 ℃
Ambient operating humidity 30 % to 80 % (With no condensation)
Ambient storage humidity 90 % or less (With no condensation)

*1 Typical value

*2 Calculated from the ratio of the full well capacity and the RMS read noise

*3 Dark current depends on cooling temperature

*4 In ultra-quiet scan

*5 Equivalent to USB 3.1 Gen 1 (SuperSpeed USB 5 Gbps)

Spectral response


Instruction manual

Contact us for more information.

  • Literature
  • Price
  • Delivery
  • Custom order
  • Demo
  • Support
  • Other

Contact us